Research & Publications

Dr. Rajiv Sinha is a UK board-certified Paediatric Nephrologist and Professor & Head, Department of Paediatric Nephrology, Institute of Child Health, Kolkata. He established the first academic Pediatric Nephrology unit and training programme in Eastern India , with a career spanning clinical care, research, teaching, and international collaboration.

Peer-Reviewed Publications
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Major Book Chapters
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International Research
Awards & Fellowships
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Highest Journal Impact
Factor (Kidney International)
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Featured Publications

Nephrotic Syndrome & Rituximab

  • Rituximab Dosage Study (2025): A multicentre randomized controlled trial comparing single vs. double dose Rituximab for steroid-dependent nephrotic syndrome.
  • Levamisole Treatment (2024): Open-label randomized study on daily vs. alternate-day levamisole in pediatric nephrotic syndrome.
  • COVID-19 Impact: Research on the impact of the pandemic on Rituximab use in difficult nephrotic syndrome cases.

Kidney Transplantation

  • Genomics in Transplant: Utilizing Next-Generation Sequencing (NGS) for pre-transplantation workup in resource-constrained settings.
  • Dysfunctional Tracts: Experiences in pediatric kidney transplantation into dysfunctional lower urinary tracts.
  • Post-Transplant Care: Long-term outcomes and CKD parameters following pediatric renal transplantation.

Genetics & Tubulopathy

  • East India Tubulopathy Study: Whole exome sequencing and variant spectrum in children with suspected inherited renal tubular disorders.
  • COL4A Genetic Variants: High incidence of COL4A variants among children with steroid-resistant nephrotic syndrome in Eastern India.

Textbook Contributions

  • Nephrology Section:

    The Science of Paediatrics: MRCPCH Mastercourse (Elsevier, 2017).

  • Haematuria:

    PG Textbook of Pediatrics (Jaypee Brothers, 2015).

  • Chronic Kidney Disease:

    Principles and Practice of Pediatric Nephrology (Jaypee Brothers, 2013).

  • Nutrition in CKD:

    Specialized chapter on nutritional management for children with renal failure.

International Presentations

  • IPNA Congress (Brazil, Shanghai, Istanbul):

    Oral presentations on antibiotic use and transplant outcomes.

  • European Society (ESPN):

    Research presentations in Glasgow and Lyon.

  • American Society (ASN):

    Research on sleep disturbances in children with Chronic Kidney Disease.

Clinical Audits

  • Antibiotic Prophylaxis:

    Audit of antibiotics during micturating cystourethrograms (Kolkata, 2015).

  • Renal Biopsies:

    Comprehensive review of biopsy complications in Eastern India.

  • Nocturnal Enuresis:

    Comparison of clinic management with international ERIC guidelines.

International Presentations

 

  • “Single- versus Divided-Dose Prednisolone for the First Episode of Nephrotic Syndrome in Children: An Open-Label RCT.” – Asian Congress of Pediatric Nephrology, Dubai (2023)
  • “Paediatric kidney transplantation into dysfunctional lower urinary tract: A single center experience from Eastern India” – International Pediatric Transplant Association Congress, Vancouver (2019)
  • “Targeted Next-Generation Sequencing (NGS) – a useful tool in pre-transplantation work up even in resource constrained set ups” – International Pediatric Transplant Association Congress, Vancouver (2019)
  • “A randomised controlled trial on use of antibiotics in micturating cystourethrogram” – Annual Conference of IPNA, Iguassu, Brazil (2016) and Annual Conference of ESPN, Glasgow (2017)
  • “A retrospective study of utility of rituximab in children with difficult nephritic syndrome” – Asian Congress of Pediatric Nephrology, New Delhi (2014)
  • “A retrospective study of renal biopsy in children” – Asian Congress of Pediatric Nephrology, New Delhi (2014)
  • “A prospective evaluation of investigations for urinary tract infection in children less than 5 years of age as per ISPN guidelines” – IPNA Conference, Shanghai (2013)
  • “Prospective analysis of utility and feasibility of Ambulatory Blood Pressure Monitoring (ABPM) service in India” – IPNA Conference, Shanghai (2013)
  • “Conversion to monotherapy maintenance immunosuppression in paediatric renal transplant recipients” – European Transplant Fellow Workshop (2010)
  • “Prevalence of Chronic Kidney Disease in paediatric renal transplants” – International Paediatric Transplant Association meeting, Istanbul (2009)
  • “Mono-therapy immunosuppression maintenance in paediatric renal transplantation” – British Transplant Society Annual Meeting, Liverpool (2009)
  • “Sleep disturbances among children and adolescents with non-dialysis dependent chronic kidney disease” – American Society of Nephrology (ASN), Philadelphia (2008)
  • “Chronic Kidney Disease in paediatric renal transplants – A KDOQI perspective” – European Society of Paediatric Nephrology, Lyon (2008)
  • “Long term outcome of acute renal failure among children from a developing country” – Royal College of Paediatrics and Child Health Annual Spring Meeting, York (2008)

Publications & Contributions

Year Publication Title Journal Dr. Sinha's Contribution
2025 Single vs. double dose of rituximab for steroid-dependent nephrotic syndrome: a randomized controlled trial Pediatr Nephrol Lead Investigator & Corresponding Author
2023 Presentation and outcome of pediatric lupus nephritis in Eastern India Lupus Senior Research Supervisor
2021 Use of rituximab in paediatric nephrology Arch Dis Child Expert Subject Reviewer
2017 Prolonged intermittent renal replacement therapy in children Pediatr Nephrol Primary Researcher
2013 Pediatric Chronic Kidney Disease (Chapter 57) IAP Textbook Contributing Book Author
2009 Ten-year follow-up of children after acute renal failure Nephrol Dial Trans Lead Clinical Researcher
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